
Wheel running exercise modified the gut microbiota composition in adult rats. ∗∗∗ p < 0.001. Abbreviations: EX (exercise); SED (sedentary).

Exercise induces changes in tryptophan metabolism by gut microbes associated with hippocampal function in adult rats
Voluntary exercise reshapes gut microbiota and tryptophan metabolism, with consequences for the hippocampus, the brain's memory center
We observed exercise-driven changes in tryptophan-metabolizing gut bacteria, shifts in circulating metabolites, and reduced aryl hydrocarbon receptor expression in the dorsal hippocampus.”— Professor Yvonne M. Nolan, University College Cork
CORK, COUNTY CORK, IRELAND, March 10, 2026 /EINPresswire.com/ -- Something happens when a rat starts running. Not just the obvious things, the faster heart, the warming muscles, the rhythmic percussion of paws against the wheel. Something quieter. Something that begins in the coiled darkness of